Bioprocess Development
BioFactura’s biopharmaceutical industry experience is grounded in bioprocess development, scale-up, and manufacturing. The Company has capabilities to develop a broad range of upstream bioprocesses in bacterial, yeast, and mammalian cell culture expression systems. This includes the development of expression vectors and cell lines through medium optimization and process scale-up. BioFactura is also highly experienced in developing downstream recovery and purification processes. Steps may include centrifugation, micro-/ultra-filtration, chromatography, and viral inactivation. The Company is also well versed in the development of initial formulations of investigational biologics, and in the development of in-process and release analytical assays including bioactivity methods such as viral neutralization.